FACTS ON VITAMIN B12 DEFICIENCY
FACTS ON VITAMIN B12 DEFICIENCY Vitamins are organic compounds needed for normal function, growth and maintenance. t here are two types of vitamins ( fat soluble & water soluble). Water soluble vitamin B12, also known as cyanocobolamine, is transported via the blood, stored in small amounts, and eliminated from the body through urination. The importance of vitamin B12 for healthy DNA synthesis is especially clear in tissues that are actively dividing, like the gastrointestinal tract and erythroid precursors. Once it has bonded with the intrinsic factor, it is absorbed from the distal ileum. When DNA synthesis fails to occur during the development of red blood cells, cell growth without division continues, resulting in macrocytosis that is not functional and is referred to as megaloblastic anemia or macrocytic anemia. The most common cause of this problem with red blood cell DNA synthesis is a vitamin B12 and folic acid shortage because vitamin B12 is required as a co-fac...